cobas® i 601 analyzer
With the cobas® Mass Spec solution, which includes the cobas® i 601 analyzer and the Ionify® reagents line, you can step away from tedious and complex manual mass spectrometry workflows and experience the simplicity and convenience of a streamlined end-to-end solution.
From sample preparation to result interpretation, Roche will be consolidating four technologies onto a single platform—ISE, clinical chemistry, immunochemistry, and mass spectrometry—maximizing efficiency and delivering enhanced medical value. Our solution is designed to enable smart testing through seamless physical and digital connectivity with other analytical units.
A broad assay menu of Ionify reagents is in development, complementing the clinical chemistry and immunoassay portfolio available on cobas pro integrated solutions. The assays include ready-for-use test kits with consistent performance and traceability to reference methods.
:quality(90)/)
Enhance your lab’s capabilities by complementing existing methodologies and expanding services to new patient populations and disease areas with mass spectrometry.1-3 The cobas i 601 analyzer allows you to streamline current workflows that require dedicated and specialized staff.
Contact us to discover how mass spectrometry can seamlessly integrate into your routine laboratory, enabling broader access to this transformative technology.
Benefits at a glance
:quality(90)/)
:quality(90)/)
:quality(90)/)
:quality(90)/)
:quality(90)/)
:quality(90)/)
:quality(90)/)
Integrating mass spectrometry into routine testing
Product Information
The cobas® i 601 analyzer is an integrated fully automated, random-access, software controlled clinical analyzer for paramagnetic particle-based sample preparation, liquid chromatography and mass spectrometry analysis for quantitative in-vitro determinations.
The cobas® i 601 analyzer is intended to identify naturally occurring and synthetic compounds (e.g., steroids, vitamins, and others) in human specimens by ionizing the compound under investigation and the resulting ions by means of an electrical and magnetic field according to their mass-to-charge ratio.
Featured Products
:quality(90)/)
Easy-to-use, fully automated, integrated, and standardized end-to-end solution bringing mass spectrometry to routine testing environments. It is part of cobas® pro integrated solutions, featuring a consistent design and user-friendly interface—reducing the need for extensive staff training.
:quality(90)/)
Sample loading and unloading in a five-position rack with a capacity of up to 300 samples, allowing for continuous loading. STAT port for emergency samples.
:quality(90)/)
Designed to offer a true random access buffer for samples. Holds up to 25 five-position racks (125 samples). Positions can also be dedicated for STAT rack handling.
:quality(90)/)
Purification of the analytes occurs through paramagnetic particle-based sample preparation procedures, allowing automated testing in random access mode. The reagent manager consists of 48 positions in a cooled reagent rotor, enables the loading of reagent cassettes on the fly, and features an RFID reader
:quality(90)/)
The system enables the separation of analytes via columns in ready-for-use cartridges with RFID labels. It incorporates both HPLC and rapid liquid chromatography (LC) technologies to cover different selectivities. Automatic onboard mixing of mobile phases and eight parallel channels of LC columns supports high throughput—up to 100 injections per hour—and allows for random access testing. Additionally, most system reagents can be loaded on the fly to maintain uninterrupted…
:quality(90)/)
Detection and quantification of the analytes occur in a triple quadrupole tandem mass spectrometer with electrospray ionization (ESI) technology.
References
Grebe SK, Singh RJ. LC-MS/MS in the Clinical Laboratory - Where to From Here?. Clin Biochem Rev. 2011;32(1):5-31.
Hristova J & Svinarov D. Enhancing precision medicine through clinical mass spectrometry platform. Biotechnology & Biotechnological Equipment. 2022;36(1):107-117.
Ketha SS, Singh RJ, Ketha H. Role of Mass Spectrometry in Clinical Endocrinology. Endocrinol Metab Clin North Am. 2017;46(3):593-613.
Do you have questions about our products or services? We’re here to help. Contact a Roche representative in your region.
:quality(90)/)
:quality(90)/)
:quality(90)/)