Analyzers and Reagents

Mass spectrometry is a versatile and advantageous diagnostic tool found in a clinical laboratory. It can be used in certain clinical situations, such as measuring steroid hormones in endocrinology, testing vitamin D, and monitoring immunosuppressants and therapeutic drugs. The high specificity and sensitivity of the tests can provide physicians with greater levels of clarity, which in turn can benefit patients through more precise and accurate results.

Mass spectrometry is considered a gold standard in certain clinical situations¹, but many laboratories are unable to use it because current solutions are too complex, lack integration and standardization, and require highly trained personnel. Until now, no fully automated and standardized solution was available.

With the cobas® Mass Spec solution, which includes the cobas® i 601 analyzer and the Ionify® reagents line, you can step away from tedious and complex manual mass spectrometry workflows and experience the simplicity and convenience of a streamlined end-to-end solution.

A broad assay menu of Ionify reagents is in development, complementing the clinical chemistry and immunoassay portfolio available on cobas® pro integrated solutions. The assays include ready-for-use test kits with consistent performance and traceability to reference methods.

Reference:

Rankin-Turner S. and Heaney L. (2023). CCLM 61, 873-879. Available from: https://www.degruyter.com/document/doi/10.1515/cclm-2022-0984/html

• Accurate results the first time Using patented electrochemiluminescence (ECL) technology – with one of the broadest measuring ranges in the industry. High-quality reagents, clot detection, re-run, reflex testing and carry-over protection ensure accurate results the first time.

• Quality of results Using disposable tips and cups virtually eliminates the potential for carry-over

• Empowered by cobas brand commonality Intuitive user interface and convenient liquid ready-to-use reagents are common to all cobas eanalyzers allowing minimal training and optimal productivity.

The cobas® c 513 analyzer runs the established Roche Tina-quant® HbA1c test, which is standardized according to IFCC and transferable to DCCT/NGSP in order to ensure high quality and standardized results. With no interference from most commonly known HbA1c variants, Roche’s Tina-quant® HbA1c assay delivers accurate results for risk identification and monitoring of long-term blood glucose control.  It can also be used as an aid in the diagnosis of diabetes and identifying patients who may be at risk for developing diabetes. The assay delivers results that clinicians and patients can trust.

With over 50 years of innovation in clinical chemistry, immunodiagnostics and automated diagnostic systems, Roche’s Professional Diagnostics equips diagnostic laboratories around the world with a wide portfolio of more than 220 assays to measure hundreds of different parameters in blood, serum, or urine, while minimizing costs.

Analyzers and reagents include immunology and clinical chemistry systems for commercial labs, hospital core labs, medical centers and laboratory networks. 

In Clinical Chemistry you will find information about the Roche cobas® c 503 and c 703  (cobas® pro integrated solutions) and the cobas® c 303 (cobas® pure integrated solutions). We are proud of our continuously growing pipeline of different disease management products. In addition, cobas® pro integrated solutions and cobas® pure integrated solutions use the same reagents kits for a true standardization of your laboratory.

• Enzymes and Substrates

• Specific Proteins

• TDM and DAT

• Specialty Assays

In immunology you will find information about the ECL Technology* base for the cobas® e 801 analyzer (cobas® pro integrated solutions), cobas®e 402 (cobas® pure integrated solutions), and the cobas e 411 analyzer. We are proud of our continuously growing pipeline of different Disease Management products.  In addition, cobas® pro integrated solutions and cobas® pure integrated solutions use the same reagents kits for a true standardization of your laboratory:

• Thyroid Function

• Fertility/Hormones

• Tumor Markers

• Cardiac Markers

• Anemia

• Infectious Disease

• Bone Markers

• Inflammation Sepsis

• Critical Care 

• Pregnancy

Since 1996 Electrochemiluminescence (ECL) technology has been Roche’s immunochemistry detection technology of choice. It was first used in the clinical laboratory on the Elecsys® 2010 analyzer with six immunoassay applications. 

Today, ECL is the most successful chemiluminescence technology with more than 75 applications and 20,000 instrument placements worldwide. No other IVD company can offer an automated detection technology that matches ECL’s unique blend of controlled reaction, precision and sensitivity, low sample volume, wide measuring range and rapid measurement.